... 5, the first quarter of the NFL season is in the books. We should have a pretty good idea of what most of the players in the NFL are capable of. 

That being said, one of the toughest things to predict in the NFL is the big play. A running back rips off a 40-yard run, or a wideout or tight end hauls in a deep pass down the sideline for a monster gain; those are the big plays we're talking about. The kind that cause players to end their days with big yardage totals, even if the touchdowns aren't there.

These 20 players are the ones most likely to have a huge game in Week 5. We explain why they put up so many yards, who their matchup is, and what their final yardage totals will probably be. 

Let's get to the picks.

Read Complete Article at Bleacher Report - NFL